Document Type

Honors Project

Publication Date

6-13-2025

Abstract

This honors project addresses the lack of inclusive skincare formulations by developing a scientifically grounded skincare line with an antioxidant-rich serum, moisturizer, and cleanser tailored to support diverse skin types, particularly melanin-rich skin. The serum combines strawberry extract powder, Manuka honey, niacinamide, green tea extract, and humectants to promote hydration, antioxidant protection, and skin barrier reinforcement. Formulated with a stable pH of 5.0–5.5 and an effective preservative system, the product was tested through non-animal, biologically relevant models.

A UV protection assay using HEK293 cells demonstrated that the serum significantly reduces oxidative damage, increasing post-exposure cell viability to 80%, compared to 9–10% in untreated controls. Additional experiments currently ongoing; include a banana peel assay for moisture retention and oxidative browning, and an egg yolk membrane test to simulate lipid barrier protection under environmental stress. These models are chosen to uphold ethical standards and reduce reliance on animal testing.

This project merges biochemistry with cosmetic science to produce an inclusive, ethically tested, and functionally effective skincare products. The research not only supports the serum’s efficacy in combating oxidative stress and dehydration but also contributes to sustainable and inclusive innovation in skincare.

Level of Honors

magna cum laude

Department

Chemistry

Advisor

Kelly J. Culhane

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Included in

Chemistry Commons

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